药物化学系

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刘昕

作者:金飞     日期:2023-10-17   点击数:2486  

师资介绍

刘昕,男,汉族,1987.8,理学博士,副教授,硕士生导师

研究方向:

超分子纳米药物的设计合成及诊疗一体化研究

基金项目:

1、 国家自然科学基金青年项目,项目号:2200113330

2、 南通市科技计划项目,项目号:JC20200753万

科研成果:

以第一作者/通讯作者在ACS Applied Materials & InterfacesChemistry of MaterialsJournal of Colloid and Interfaces ScienceChinese Chemical LettersChemical Communications等国际期刊上发表论文多篇。

代表性论文(近五年):

1. Xin Liu*, Ji Liu, Qin Xu, Weizhi Tao, Xudong Xie, Chi Meng, Qinbei Zhou, Yanan Zhang, Yong Ling*. A versatile supramolecular nanoagent for three-pronged boosting chemodynamic therapy, J. Colloid Interface Sci., 2023, 648, 994-1005.

2. Chi Meng, Xudong Xie, Jianqiang Qian, Weizhi Tao, Hongmei Wu, Dongliang Ji, Ge Gao, Ruojia Wang, Changchun Ling, Yanan Zhang, Xin Liu*, Yong Ling*. TME-targeting nano-theranostic agent for NIR fluorescence diagnosis and O2-economized PDT-based multimodal synergistic therapy. Mater. Des., 2023, 233, 112251.

3. Xin Liu*, Ji Liu, Chi Meng, Peng Zhu, Xiao Liu, Jianqiang Qian, Shijia Ling, Yanan Zhang, Yong Ling*. Pillar[6]arene-based supramolecular nanocatalysts for synergistically enhanced chemodynamic therapy by the intracellular cascade reaction. ACS Appl. Mater. Interfaces, 2021, 13, 53574-53585.

4. Xin Liu*, Chi Meng, Guiqing Ji, Ji Liu, Peng Zhu, Jianqiang Qian, Shun-Xing Zhu, Yanan Zhang, Yong Ling*. Tumor microenvironment-activatable Boolean logic supramolecular nanotheranostics based on a pillar[6]arene for tumor hypoxia imaging and multimodal synergistic therapy, Mater. Chem. Front., 2021, 5, 5846.

5. Peng Zhu, Weidan Luo, Jianqiang Qian, Chi Meng, Wenpei Shan, Zhongyuan Xu, Wei Zhang, Xin Liu*, Yong Ling*. GSH/ROS dual-responsive supramolecular nanoparticles based on pillar[6]arene and betulinic acid prodrug for chemo–chemodynamic combination therapy, Molecules, 2021, 26, 6900.

6. Xin Liu, Kaiya Wang, Marlen Externbrink, Jochen Niemeyer, Michael Giese, Xiao-Yu Hu*. Control of secondary structure and morphology of peptide– guanidiniocarbonylpyrrole conjugates by variation of the chain length, Chin. Chem. Lett., 2020, 31, 1239-1242.